All matter of perception. Mean as in terrible, i.e Saddam Hussein was mean tyrrant. Mean as in a compliment, i..e that David Beckham can play a mean soccer game. Mean as in Math, as in I skipped math class, I cannot describe what mean is.
Now if a female is the origin of the conversation, it probably was a synonym for lack of emotion. Example: My boyfriend just stepped on my cat's tail and didn't apologize to my cat. He's mean!